Is Spero Therapeutics Stock a Good Investment?

Spero Therapeutics Investment Advice

  SPRO
To provide specific investment advice or recommendations on Spero Therapeutics stock, we recommend investors consider the following general factors when evaluating Spero Therapeutics. This will help you to make an informed decision on whether to include Spero Therapeutics in one of your diversified portfolios:
  • Examine Spero Therapeutics' financial health by looking at its balance sheet, income statement, and cash flow statement. Analyze key financial ratios, such as Price-to-Earnings (P/E), Price-to-Sales (P/S), and Price-to-Book (P/B), to determine whether the stock is fairly valued or over/undervalued.
  • Research Spero Therapeutics' leadership team and their track record. Good management can help Spero Therapeutics navigate difficult times and make strategic decisions that benefit shareholders and increases its net worth.
  • Consider the overall health of the Biotechnology space and any emerging trends that could impact Spero Therapeutics' business and its evolving consumer preferences.
  • Compare Spero Therapeutics' performance and market position to its competitors. Analyze how Spero Therapeutics is positioned in terms of product offerings, innovation, and market share.
  • Check if Spero Therapeutics pays a dividend and its dividend yield and payout ratio.
  • Review what financial analysts are saying about Spero Therapeutics' stock and their price targets. However, remember that analysts' opinions can vary, and their predictions may not always be accurate.
It's important to note that investing in Spero Therapeutics stock, carries risks, and you should carefully consider your investment goals and risk tolerance before making any investment decisions. Also, remember that it's important for investors to have a long-term perspective and a well-diversified portfolio to manage the impact of stock market volatility on their investments. Below is a detailed guide on how to decide if Spero Therapeutics is a good investment.
 
Sell
 
Buy
Strong Sell
We provide advice to complement the current expert consensus on Spero Therapeutics. Our dynamic recommendation engine harnesses a multidimensional algorithm to analyze the firm's potential to grow using all technical and fundamental data available at the time. To make sure Spero Therapeutics is not overpriced, please validate all Spero Therapeutics fundamentals, including its price to earning, book value per share, current liabilities, as well as the relationship between the net income and beta . As Spero Therapeutics appears to be a penny stock we also recommend to double-check its number of shares shorted numbers.

Market Performance

Very WeakDetails

Volatility

Very riskyDetails

Hype Condition

Low keyDetails

Current Valuation

UndervaluedDetails

Odds Of Distress

LowDetails

Economic Sensitivity

Slowly supersedes the marketDetails

Investor Sentiment

AlarmedDetails

Analyst Consensus

BuyDetails

Financial Strenth (F Score)

HealthyDetails

Financial Leverage

Not RatedDetails

Reporting Quality (M-Score)

Possible ManipulatorDetails

Examine Spero Therapeutics Stock

Researching Spero Therapeutics' stock involves analyzing various aspects of the company and its industry to make an informed investment decision. The key areas to focus on are fundamentals, business model and competitive advantage. It is also important to analyze trends in revenue, net income, and cash flow, as well as key financial ratios, such as price-to-earnings (P/E), price-to-sales (P/S), and debt-to-equity (D/E). About 24.0% of the company outstanding shares are owned by corporate insiders. The company has price-to-book ratio of 0.68. Typically companies with comparable Price to Book (P/B) are able to outperform the market in the long run.
To determine if Spero Therapeutics is a good investment, evaluating the company's potential for future growth is also very important. This may include expanding into new markets, launching new products or services, or improving operational efficiency. Companies with strong growth prospects can be more attractive investments. This aspect of the research should be conducted in the context of the overall market and industry in which the company operates and should include an analysis of growth potential, competitive landscape, and any regulatory or economic factors that could impact the business. Some of the essential points regarding Spero Therapeutics' research are outlined below:
Spero Therapeutics generated a negative expected return over the last 90 days
Spero Therapeutics has some characteristics of a very speculative penny stock
Spero Therapeutics has high historical volatility and very poor performance
Spero Therapeutics currently holds about 45.4 M in cash with (32.99 M) of positive cash flow from operations. This results in cash-per-share (CPS) ratio of 1.29, which can makes it an attractive takeover target, given it will continue generating positive cash flow.
Roughly 24.0% of the company outstanding shares are owned by corporate insiders
Latest headline from globenewswire.com: Spero Therapeutics to Report Fourth Quarter and Full Year 2024 Financial Results and Provide Business Update on Thursday, March 27, 2025

Spero Therapeutics Quarterly Cash And Short Term Investments

76.29 Million

Spero Therapeutics uses earnings reports to provide investors with an update of all three financial statements, including the income statement, the balance sheet, and the cash flow statement. Therefore, it is also crucial when considering investing in Spero Therapeutics. Every quarterly earnings report provides investors with an overview of sales, expenses, and net income for the most recent period. It also may provide a comparison to Spero Therapeutics' previous reporting period. The quarterly earnings reports are usually disseminated to the public via Form 10-Q, which is a legal document filed with the Securities and Exchange Commission every quarter.
4th of April 2024
Upcoming Quarterly Report
View
9th of May 2024
Next Financial Report
View
31st of December 2023
Next Fiscal Quarter End
View
4th of April 2024
Next Fiscal Year End
View
30th of September 2023
Last Quarter Report
View
31st of December 2022
Last Financial Announcement
View
Earnings surprises can significantly impact Spero Therapeutics' stock price both in the short term and over time. Negative earnings surprises usually result in a price decline. However, it has been seen that positive earnings surprises lead to an immediate rise in a stock's price and a gradual increase over time. This is why we often hear news about some companies beating earning projections. Financial analysts spend a large amount of time predicting earnings per share (EPS) along with other important future indicators. Many analysts use forecasting models, management guidance, and additional fundamental information to derive an EPS estimate. Below are the table of largest EPS Surprises Spero Therapeutics' investors have experienced.
Reported
Fiscal Date
Estimated EPS
Reported EPS
Surprise
2022-11-14
2022-09-30-0.3-0.33-0.0310 
2024-08-05
2024-06-30-0.38-0.330.0513 
2023-11-13
2023-09-30-0.030.040.07233 
2023-05-11
2023-03-31-0.33-0.250.0824 
2018-08-09
2018-06-30-0.77-0.690.0810 
2019-08-08
2019-06-30-0.65-0.74-0.0913 
2019-11-04
2019-09-30-0.85-0.95-0.111 
2023-08-10
2023-06-30-0.34-0.230.1132 

Know Spero Therapeutics' Top Institutional Investors

Have you ever been surprised when a price of an equity instrument such as Spero Therapeutics is soaring high without any particular reason? This is usually happening because many institutional investors are aggressively trading Spero Therapeutics backward and forwards among themselves. Spero Therapeutics' institutional investor refers to the entity that pools money to purchase Spero Therapeutics' securities or originate loans. Institutional investors include commercial and private banks, credit unions, insurance companies, pension funds, hedge funds, endowments, and mutual funds. Operating companies that invest excess capital in these types of assets may also be included in the term and may influence corporate governance by exercising voting rights in their investments.
Shares
Bridgeway Capital Management, Llc2024-12-31
184.8 K
Citadel Advisors Llc2024-12-31
172.9 K
State Street Corp2024-12-31
148.9 K
Dafna Capital Management Llc2024-12-31
125 K
Northern Trust Corp2024-12-31
86.4 K
Jpmorgan Chase & Co2024-12-31
61.6 K
Squarepoint Ops Llc2024-12-31
55.1 K
Jane Street Group Llc2024-12-31
52.9 K
Prudential Financial Inc2024-12-31
49.2 K
Anson Funds Management Lp2024-12-31
3.8 M
Pfizer Inc2024-12-31
2.4 M
Note, although Spero Therapeutics' institutional investors appear to be way more sophisticated than retail investors, it remains unclear if professional active investment managers can reliably enhance risk-adjusted returns by an amount that exceeds fees and expenses.

Spero Therapeutics' market capitalization trends

The company currently falls under 'Micro-Cap' category with a current market capitalization of 44.82 M.

Market Cap

135.7 Million

Spero Therapeutics' profitablity analysis

Last ReportedProjected for Next Year
Return On Tangible Assets 0.11  0.12 
Return On Capital Employed 0.13  0.14 
Return On Assets 0.11  0.12 
Return On Equity 0.19  0.20 
The company has Profit Margin (PM) of 0.03 %, which maeans that even a very small decline in it revenue will erase profits resulting in a net loss. This is way below average. Similarly, it shows Operating Margin (OM) of (1.38) %, which suggests for every $100 dollars of sales, it generated a net operating loss of $1.38.
Determining Spero Therapeutics' profitability involves analyzing its financial statements and using various financial metrics to determine if Spero Therapeutics is a good buy. For example, gross profit margin measures Spero Therapeutics' profitability after accounting for the cost of goods sold, while net profit margin measures profitability after accounting for all expenses. Other important metrics include return on assets, return on equity, and free cash flow. By reviewing multiple sources and metrics, you can gain a complete picture of Spero Therapeutics' profitability and make more informed investment decisions.

Evaluate Spero Therapeutics' management efficiency

As of the 24th of March 2025, Return On Tangible Assets is likely to grow to 0.12. Also, Return On Capital Employed is likely to grow to 0.14. At this time, Spero Therapeutics' Return On Assets are very stable compared to the past year. As of the 24th of March 2025, Asset Turnover is likely to grow to 0.50, while Total Assets are likely to drop about 119.9 M. Spero Therapeutics' management efficiency ratios could be used to measure how well Spero Therapeutics manages its routine affairs as well as how well it operates its assets and liabilities.
Last ReportedProjected for Next Year
Book Value Per Share 2.33  2.22 
Tangible Book Value Per Share 2.33  2.22 
Enterprise Value Over EBITDA 0.23  0.25 
Price Book Value Ratio 0.83  0.79 
Enterprise Value Multiple 0.23  0.25 
Price Fair Value 0.83  0.79 
Enterprise ValueM5.7 M
The strategic initiatives led by Spero Therapeutics' management are central to its market success. By analyzing these initiatives, we provide a clear picture of the stock's growth prospects.
Beta
0.686

Basic technical analysis of Spero Stock

As of the 24th of March, Spero Therapeutics has the Risk Adjusted Performance of (0.07), variance of 15.28, and Coefficient Of Variation of (1,186). In relation to fundamental indicators, the technical analysis model makes it possible for you to check existing technical drivers of Spero Therapeutics, as well as the relationship between them.

Spero Therapeutics' insider trading activities

Some recent studies suggest that insider trading raises the cost of capital for securities issuers and decreases overall economic growth. Trading by specific Spero Therapeutics insiders, such as employees or executives, is commonly permitted as long as it does not rely on Spero Therapeutics' material information that is not in the public domain. Local jurisdictions usually require such trading to be reported in order to monitor insider transactions. In many U.S. states, trading conducted by corporate officers, key employees, directors, or significant shareholders must be reported to the regulator or publicly disclosed, usually within a few business days of the trade. In these cases Spero Therapeutics insiders are required to file a Form 4 with the U.S. Securities and Exchange Commission (SEC) when buying or selling shares of their own companies.
 
Timothy Keutzer over two weeks ago
Acquisition by Timothy Keutzer of 2661 shares of Spero Therapeutics subject to Rule 16b-3
 
Mahadevia Ankit over a month ago
Disposition of 55260 shares by Mahadevia Ankit of Spero Therapeutics at 0.78 subject to Rule 16b-3
 
Shukla Sath over a month ago
Acquisition by Shukla Sath of 751407 shares of Spero Therapeutics subject to Rule 16b-3
 
Aquilo Capital Management, Llc over two months ago
Acquisition by Aquilo Capital Management, Llc of 16885 shares of Spero Therapeutics at 8.7884 subject to Rule 16b-3
 
Aquilo Capital, L.p. over three months ago
Acquisition by Aquilo Capital, L.p. of 727 shares of Spero Therapeutics at 5.235 subject to Rule 16b-3
 
Esther Rajavelu over three months ago
Disposition of 17245 shares by Esther Rajavelu of Spero Therapeutics at 1.3 subject to Rule 16b-3
 
Tregoning Kathleen over three months ago
Acquisition by Tregoning Kathleen of 35604 shares of Spero Therapeutics at 1.52 subject to Rule 16b-3
 
Gsk Plc over six months ago
Discretionary transaction by Gsk Plc of tradable shares of Spero Therapeutics subject to Rule 16b-3
 
Esther Rajavelu over six months ago
Acquisition by Esther Rajavelu of 300000 shares of Spero Therapeutics subject to Rule 16b-3
 
Shukla Sath over six months ago
Disposition of 2757 shares by Shukla Sath of Spero Therapeutics at 1.35 subject to Rule 16b-3
 
Pottage John C Jr over six months ago
Acquisition by Pottage John C Jr of 20000 shares of Spero Therapeutics subject to Rule 16b-3
 
Shukla Sath over six months ago
Disposition of 14800 shares by Shukla Sath of Spero Therapeutics at 1.32 subject to Rule 16b-3

Spero Therapeutics' Outstanding Corporate Bonds

Spero Therapeutics issues bonds to finance its operations. Corporate bonds make up one of the largest components of the U.S. bond market, which is considered the world's largest securities market. Spero Therapeutics uses the proceeds from bond sales for a wide variety of purposes, including financing ongoing mergers and acquisitions, buying new equipment, investing in research and development, buying back their own stock, paying dividends to shareholders, and even refinancing existing debt. Most Spero bonds can be classified according to their maturity, which is the date when Spero Therapeutics has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Understand Spero Therapeutics' technical and predictive indicators

Using predictive indicators to make investment decisions involves analyzing Spero Therapeutics' various financial and market-based factors to help forecast future trends and identify investment opportunities. Select the indicators that are most relevant to your investment strategy. Each indicator has its own strengths and weaknesses, so it's essential to combine multiple indicators to get a more comprehensive view of the market and reduce the risk of making poor decisions based on limited data.

Consider Spero Therapeutics' intraday indicators

Spero Therapeutics intraday indicators are useful technical analysis tools used by many experienced traders. Just like the conventional technical analysis, daily indicators help intraday investors to analyze the price movement with the timing of Spero Therapeutics stock daily movement. By combining multiple daily indicators into a single trading strategy, you can limit your risk while still earning strong returns on your managed positions.
Spero Therapeutics time-series forecasting models is one of many Spero Therapeutics' stock analysis techniques aimed to predict future share value based on previously observed values. Time-series forecasting models ae widely used for non-stationary data. Non-stationary data are called the data whose statistical properties e.g. the mean and standard deviation are not constant over time but instead, these metrics vary over time. These non-stationary Spero Therapeutics' historical data is usually called time-series. Some empirical experimentation suggests that the statistical forecasting models outperform the models based exclusively on fundamental analysis to predict the direction of the market movement and maximize returns from investment trading.

Spero Stock media impact

Far too much social signal, news, headlines, and media speculation about Spero Therapeutics that are available to investors today. That information is available publicly through Spero media outlets and privately through word of mouth or via Spero internal channels. However, regardless of the origin, that massive amount of Spero data is challenging to quantify into actionable patterns, especially for investors that are not very sophisticated with ever-evolving tools and techniques used in the investment management field.
A primary focus of Spero Therapeutics news analysis is to determine if its current price reflects all relevant headlines and social signals impacting the current market conditions. A news analyst typically looks at the history of Spero Therapeutics relative headlines and hype rather than examining external drivers such as technical or fundamental data. It is believed that price action tends to repeat itself due to investors' collective, patterned thinking related to Spero Therapeutics' headlines and news coverage data. This data is often completely overlooked or insufficiently analyzed for actionable insights to drive Spero Therapeutics alpha.

Spero Therapeutics Sentiment by Major News Outlets

Investor sentiment, mood or attitude towards Spero Therapeutics can have a significant impact on its stock price or the market as a whole. This sentiment can be positive or negative, and various factors, such as economic indicators, news events, or market trends, can influence it. When investor sentiment is positive, investors are more likely to buy stocks, increasing demand and increasing the stock price. Positive investor sentiment can be driven by good news about the company or the broader market, such as solid earnings reports or positive economic data.
Note that negative investor sentiment can cause investors to sell stocks, leading to a decrease in demand and a drop in the stock price. Negative sentiment can be driven by factors such as poor earnings reports, negative news about the company or industry, or broader economic concerns. It's important to note that investor sentiment is just one of many factors that can affect stock prices. Other factors, such as company performance, industry trends, and global economic conditions, can also play a significant role in determining the value of a stock.

Spero Therapeutics Corporate Management

Satyavrat CFACFO TreasurerProfile
James BradyChief OfficerProfile
Ted JenkinsVP RelationsProfile
Ian CritchleyHead MicrobiologyProfile
Susannah WalpoleHead OperationsProfile
When determining whether Spero Therapeutics offers a strong return on investment in its stock, a comprehensive analysis is essential. The process typically begins with a thorough review of Spero Therapeutics' financial statements, including income statements, balance sheets, and cash flow statements, to assess its financial health. Key financial ratios are used to gauge profitability, efficiency, and growth potential of Spero Therapeutics Stock. Outlined below are crucial reports that will aid in making a well-informed decision on Spero Therapeutics Stock:
Check out World Market Map to better understand how to build diversified portfolios, which includes a position in Spero Therapeutics. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in metropolitan statistical area.
To learn how to invest in Spero Stock, please use our How to Invest in Spero Therapeutics guide.
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Is Biotechnology space expected to grow? Or is there an opportunity to expand the business' product line in the future? Factors like these will boost the valuation of Spero Therapeutics. If investors know Spero will grow in the future, the company's valuation will be higher. The financial industry is built on trying to define current growth potential and future valuation accurately. All the valuation information about Spero Therapeutics listed above have to be considered, but the key to understanding future value is determining which factors weigh more heavily than others.
Quarterly Earnings Growth
0.753
Earnings Share
0.08
Revenue Per Share
1.984
Quarterly Revenue Growth
(0.47)
Return On Assets
(0.01)
The market value of Spero Therapeutics is measured differently than its book value, which is the value of Spero that is recorded on the company's balance sheet. Investors also form their own opinion of Spero Therapeutics' value that differs from its market value or its book value, called intrinsic value, which is Spero Therapeutics' true underlying value. Investors use various methods to calculate intrinsic value and buy a stock when its market value falls below its intrinsic value. Because Spero Therapeutics' market value can be influenced by many factors that don't directly affect Spero Therapeutics' underlying business (such as a pandemic or basic market pessimism), market value can vary widely from intrinsic value.
In summary, please note that there is a difference between Spero Therapeutics' value and its price, as these two are different measures arrived at by various means. Investors typically determine if Spero Therapeutics is a good investment by looking at such factors as earnings, sales, fundamental and technical indicators, competition as well as analyst projections. However, Spero Therapeutics' price is the amount at which it trades on the open market and represents the number that a seller and buyer find agreeable to each party.