Ionis Pharmaceuticals Stock Buy Hold or Sell Recommendation
| IONS Stock | USD 32.96 0.06 0.18% |
Given the investment horizon of 90 days and your above-average risk tolerance, our recommendation regarding Ionis Pharmaceuticals is 'Strong Hold'. A buy or sell recommendation is an automated directive regarding whether to purchase or sell Ionis Pharmaceuticals given historical horizon and risk tolerance. When we issue a 'buy' or 'sell' recommendation for Ionis Pharmaceuticals, the advice is generated through an automated system that utilizes algorithms and statistical models.
Check out Ionis Pharmaceuticals Analyst Recommendation to compare Macroaxis Buy or Sell Recommendation with the current analyst consensus. To check ratings for multiple equity instruments, please use the Instant Ratings tool. For more information on how to buy Ionis Stock please use our How to Invest in Ionis Pharmaceuticals guide. Note, we conduct extensive research on individual companies such as Ionis and provide practical buy, sell, or hold advice based on investors' constraints. Ionis Pharmaceuticals. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in board of governors.
Ionis |
Execute Ionis Pharmaceuticals Buy or Sell Advice
The Ionis recommendation should be used to complement the buy-or-sell advice compiled from the current analysts' consensus on Ionis Pharmaceuticals. Macroaxis does not own or have any residual interests in Ionis Pharmaceuticals or other equities on which the buy-or-sell advice is provided. Please provide your input below to execute Ionis Pharmaceuticals' advice using the current market data and latest reported fundamentals.
Time Horizon
Risk Tolerance
 |  |
Strong Hold
Market Performance | Very Weak | Details | |
Volatility | Very steady | Details | |
Hype Condition | Low key | Details | |
Current Valuation | Undervalued | Details | |
Odds Of Distress | Below Average | Details | |
Economic Sensitivity | Follows the market closely | Details | |
Investor Sentiment | Alarmed | Details | |
Analyst Consensus | Strong Buy | Details | |
Financial Strenth (F Score) | Frail | Details | |
Financial Leverage | Not Rated | Details | |
Reporting Quality (M-Score) | Unlikely Manipulator | Details |
Ionis Pharmaceuticals Trading Alerts and Improvement Suggestions
| Ionis Pharmaceuticals generated a negative expected return over the last 90 days | |
| The company reported the previous year's revenue of 705.14 M. Net Loss for the year was (453.9 M) with loss before overhead, payroll, taxes, and interest of (207.61 M). | |
| Ionis Pharmaceuticals currently holds about 2.04 B in cash with (500.95 M) of positive cash flow from operations. This results in cash-per-share (CPS) ratio of 14.36. | |
| Ionis Pharmaceuticals has a frail financial position based on the latest SEC disclosures | |
| Over 99.0% of the company shares are owned by institutional investors | |
| Latest headline from finance.yahoo.com: Ionis Pharmaceuticals Partners With Japan-Based Ono Pharmaceutical For Rare Blood Disease Drug In Over 800 Million Deal |
Ionis Pharmaceuticals current analysts advice
We track the performance of the top 100 financial experts across various large and mid-size financial boutiques. Ionis analyst recommendations are determined by taking all analyst recommendations and averaging them as Strong Buy, Buy, Hold, Strong Sell or Sell. There is no one specific way to measure analysis performance other than comparing it to the past results via a very sophisticated attribution analysis. Ionis analyst consensus and target price projections should be used in combination with other traditional techniques such as stock price forecasting, technical analysis, earnings estimate, and various momentum models.
Average Consensus Strong Buy
The consensus estimates and target price estimation comprises individual analyst assessments, and may or may not mutch the Macroaxis buy or sell advice. It is determined by taking an average of all analyst recommendations and classifying them as Strong Buy, Buy, Hold, or Sell.
Ionis Pharmaceuticals Returns Distribution Density
The distribution of Ionis Pharmaceuticals' historical returns is an attempt to chart the uncertainty of Ionis Pharmaceuticals' future price movements. The chart of the probability distribution of Ionis Pharmaceuticals daily returns describes the distribution of returns around its average expected value. We use Ionis Pharmaceuticals price's Value At Risk and its Upside Potential as a relative measure of the distribution. The graph of the distribution of Ionis Pharmaceuticals returns is essential to provide solid investment advice for Ionis Pharmaceuticals.
| Mean Return | -0.19 | Value At Risk | -3.8 | Potential Upside | 4.42 | Standard Deviation | 2.50 |
Return Density |
| Distribution |
Investment risk management requires an estimate of the probability of extreme price changes. Therefore, the correct representation of the distribution of Ionis Pharmaceuticals historical returns presented in an easy-to-digest graphical form helps investors and money managers understand the risk-reward trade-off of different investement strategies.
Ionis Stock Institutional Investors
The Ionis Pharmaceuticals' institutional investors refer to entities that pool money to purchase Ionis Pharmaceuticals' securities or originate loans. These institutional investors include commercial and private banks, credit unions, insurance companies, pension funds, hedge funds, endowments, and mutual funds.
| Shares | Geode Capital Management, Llc | 2024-12-31 | 2.7 M | Citadel Advisors Llc | 2024-12-31 | 2.2 M | Deep Track Capital, Lp | 2024-12-31 | 1.9 M | Ubs Group Ag | 2024-12-31 | 1.9 M | Macquarie Group Ltd | 2024-12-31 | 1.8 M | Norges Bank | 2024-12-31 | 1.7 M | Clearbridge Advisors, Llc | 2024-12-31 | 1.6 M | Charles Schwab Investment Management Inc | 2024-12-31 | 1.5 M | Two Sigma Advisers, Llc | 2024-12-31 | 1.3 M | Fmr Inc | 2024-12-31 | 22.7 M | Vanguard Group Inc | 2024-12-31 | 16.5 M |
Ionis Pharmaceuticals Cash Flow Accounts
| 2020 | 2021 | 2022 | 2023 | 2024 | 2025 (projected) | ||
| Change In Cash | (285.6M) | 471.5M | (592.7M) | 122.8M | (157.2M) | (149.3M) | |
| Free Cash Flow | (5.2M) | 12.9M | (294.5M) | (335.5M) | (546.2M) | (518.9M) | |
| Depreciation | 17.2M | 19.6M | 22.1M | 22.5M | 19.7M | 10.5M | |
| Other Non Cash Items | 35.7M | 7.7M | (134.6M) | 7.7M | 12.5M | 13.1M | |
| Capital Expenditures | 41.0M | 17.9M | 20.1M | 28.0M | 45.3M | 47.5M | |
| Net Income | (486.8M) | (28.6M) | (269.7M) | (366.3M) | (453.9M) | (431.2M) | |
| End Period Cash Flow | 397.7M | 869.2M | 276.5M | 399.3M | 242.1M | 176.1M | |
| Change To Inventory | (1.3M) | (2.8M) | 2.8M | (6.4M) | (5.1M) | (4.8M) | |
| Investments | 315.5M | 212.8M | (262.6M) | 24.7M | (134.0M) | (127.3M) | |
| Net Borrowings | (22.1M) | 313.6M | 418.3M | (50.7M) | (58.3M) | (55.4M) | |
| Change To Netincome | 161.3M | 528.8M | 130.9M | 103.0M | 118.5M | 87.2M |
Ionis Pharmaceuticals Greeks
Most traded equities are subject to two types of risk - systematic (i.e., market) and unsystematic (i.e., nonmarket or company-specific) risk. Unsystematic risk is the risk that events specific to Ionis Pharmaceuticals or Biotechnology sector will adversely affect the stock's price. This type of risk can be diversified away by owning several different stocks in different industries whose stock prices have shown a small correlation to each other. On the other hand, systematic risk is the risk that Ionis Pharmaceuticals' price will be affected by overall stock market movements and cannot be diversified away. So, no matter how many positions you have, you cannot eliminate market risk. However, you can measure a Ionis stock's historical response to market movements and buy it if you are comfortable with its volatility direction. Beta and standard deviation are two commonly used measures to help you make the right decision.
α | Alpha over Dow Jones | -0.1 | |
β | Beta against Dow Jones | 0.89 | |
σ | Overall volatility | 2.51 | |
Ir | Information ratio | -0.04 |
Ionis Pharmaceuticals Volatility Alert
Ionis Pharmaceuticals exhibits very low volatility with skewness of 0.34 and kurtosis of 0.28. Understanding different market volatility trends often help investors to time the market. Properly using volatility indicators enable traders to measure Ionis Pharmaceuticals' stock risk against market volatility during both bullish and bearish trends. The higher level of volatility that comes with bear markets can directly impact Ionis Pharmaceuticals' stock price while adding stress to investors as they watch their shares' value plummet. This usually forces investors to rebalance their portfolios by buying different financial instruments as prices fall.Ionis Pharmaceuticals Fundamentals Vs Peers
Comparing Ionis Pharmaceuticals' fundamentals to the average values of its peers is one of the most widely used and accepted methods of equity analyses. It helps to analyze Ionis Pharmaceuticals' direct or indirect competition across all of the common fundamentals between Ionis Pharmaceuticals and the related equities. This way, we can detect undervalued stocks with similar characteristics as Ionis Pharmaceuticals or determine the stocks which would be an excellent addition to an existing portfolio. Peer analysis of Ionis Pharmaceuticals' fundamental indicators could also be used in its relative valuation, which is a method of valuing Ionis Pharmaceuticals by comparing valuation metrics with those of similar companies.
| Better Than Average | Worse Than Average | Compare Ionis Pharmaceuticals to competition |
| Fundamentals | Ionis Pharmaceuticals | Peer Average |
| Return On Equity | -0.93 | -0.31 |
| Return On Asset | -0.0991 | -0.14 |
| Profit Margin | (0.64) % | (1.27) % |
| Operating Margin | (0.49) % | (5.51) % |
| Current Valuation | 4.36 B | 16.62 B |
| Shares Outstanding | 158.96 M | 571.82 M |
| Shares Owned By Insiders | 0.83 % | 10.09 % |
| Shares Owned By Institutions | 99.17 % | 39.21 % |
| Number Of Shares Shorted | 12.67 M | 4.71 M |
| Price To Earning | 101.16 X | 28.72 X |
| Price To Book | 8.91 X | 9.51 X |
| Price To Sales | 7.43 X | 11.42 X |
| Revenue | 705.14 M | 9.43 B |
| Gross Profit | (207.61 M) | 27.38 B |
| EBITDA | (475.08 M) | 3.9 B |
| Net Income | (453.9 M) | 570.98 M |
| Cash And Equivalents | 2.04 B | 2.7 B |
| Cash Per Share | 14.36 X | 5.01 X |
| Total Debt | 1.41 B | 5.32 B |
| Debt To Equity | 2.00 % | 48.70 % |
| Current Ratio | 8.18 X | 2.16 X |
| Book Value Per Share | 3.73 X | 1.93 K |
| Cash Flow From Operations | (500.95 M) | 971.22 M |
| Short Ratio | 7.45 X | 4.00 X |
| Earnings Per Share | (3.04) X | 3.12 X |
| Price To Earnings To Growth | 25.70 X | 4.89 X |
| Target Price | 59.5 | |
| Number Of Employees | 1.07 K | 18.84 K |
| Beta | 0.28 | -0.15 |
| Market Capitalization | 5.24 B | 19.03 B |
| Total Asset | 3 B | 29.47 B |
| Retained Earnings | (2.25 B) | 9.33 B |
| Working Capital | 2.31 B | 1.48 B |
Note: Acquisition by Devers Shannon L. of 22000 shares of Ionis Pharmaceuticals at 34.69 subject to Rule 16b-3 [view details]
Ionis Pharmaceuticals Market Momentum
Traders often use several daily momentume indicators to supplement a more traditional technical analysis when analyzing securities such as Ionis . With many different options, investors must choose the best indicators for them and familiarize themselves with how they work. We suggest combining traditional momentum indicators with more near-term forms of technical analysis such as Accumulation Distribution or Daily Balance Of Power. With their quantitative nature, daily value technical indicators can also be incorporated into your automated trading systems.
About Ionis Pharmaceuticals Buy or Sell Advice
When is the right time to buy or sell Ionis Pharmaceuticals? Buying financial instruments such as Ionis Stock isn't very hard. However, what challenging for most investors is doing it at the right time to beat the market. Proper market timing is something most people cannot do without sophisticated tools, which help to isolate the right opportunities. Macroaxis provides hands-on modules to deliver winning trades and diversify your portfolios on a daily basis. Most of our advising modules are very easy to use and apply.
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Additional Tools for Ionis Stock Analysis
When running Ionis Pharmaceuticals' price analysis, check to measure Ionis Pharmaceuticals' market volatility, profitability, liquidity, solvency, efficiency, growth potential, financial leverage, and other vital indicators. We have many different tools that can be utilized to determine how healthy Ionis Pharmaceuticals is operating at the current time. Most of Ionis Pharmaceuticals' value examination focuses on studying past and present price action to predict the probability of Ionis Pharmaceuticals' future price movements. You can analyze the entity against its peers and the financial market as a whole to determine factors that move Ionis Pharmaceuticals' price. Additionally, you may evaluate how the addition of Ionis Pharmaceuticals to your portfolios can decrease your overall portfolio volatility.